Sökning: "ECP"

Visar resultat 1 - 5 av 53 avhandlingar innehållade ordet ECP.

1. 1. Studies of Eosinophil Cationic Protein (ECP) in vivo and in vitro : Impact of Genetic and Posttranslational Modifications

   Författare :Jenny Eriksson; Per Venge; Agneta Trulson; Ester Boix; Uppsala universitet; []
   Nyckelord :Biomedicine; Eosinophil granulocyte; granular protein; ECP; gene polymorphism; cytotoxicity; SELDI-TOF MS; glycosylation; molecular and functional heterogeneity; fibrosis; Biomedicin;

   Sammanfattning : Eosinophil granulocytes are tissue dwelling leukocytes that are implicated in host defence, particularly against helminthic parasites; they also participate in most inflammatory disorders. Although eosinophils have important roles in host defence mechanisms, their actions can also be harmful to the host as in the allergic inflammation where lung epithelium is destructed due to the release of toxic granule proteins. LÄS MER

3. 2. Bystander Cells and Prognosis in Hodgkin Lymphoma

   Författare :Daniel Molin; Stephen J. Proctor; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin Lymphoma; Bystander cells; Eosinophilic granulocytes; Eosinophil cationic protein ECP ; Mast cells; Prognosis; Early and Intermediate stage; Onkologi; Hodgkin lymfom; eosinofila granulocyter; ECP; mast celler; prognos; tidiga och intermediära stadier; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : Hodgkin lymphoma (HL) is characterised histologically by a minority of malignant Hodgkin and Reed-Sternberg (HRS) cells surrounded by benign cells, and clinically by a relatively good prognosis. The treatment, however, leads to a risk of serious side effects. LÄS MER

4. 3. Mechanisms of granule protein mobiliation in blood eosinophils

   Författare :Malgorzata Karawajczyk; Uppsala universitet; []
   Nyckelord :Medical sciences; eosinophil granule proteins; ECP; EPX; EPO; serum levels; piecemeal degranulation; release; ultrastructure; subcellular fractionation; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Serum levels of eosinophil granule proteins namely ECP, EPO and EPX, which are stored in the matrix of specific granules, were shown to correlate with the course of disease in disorders involving eosinophils. The concentration of eosinophil proteins in serum is the result of their release in vivo and ex vivo during the sampling procedure. LÄS MER

5. 4. Clinical and Experimental Studies on Inflammatory Bowel Disease with special emphasis on Collagenous Colitis

   Författare :Michael Wagner; Marie Carlson; Maria Lampinen; Per Sangfelt; Erik Hertervig; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagenous colitis; inflammatory bowel disease; ulcerative colitis; Crohn´s disease; faecal markers; eosinophil; T-cells; ECP; EPX; MPO; calprotectin; flowcytometry; chromogranin A; chromogranin B; secretoneurin; budesonide; Gastroenterology; Gastroenterologi; Medicin; Medicine;

   Sammanfattning : This thesis describes studies in patients with inflammatory bowel disease (IBD) and collagenous colitis (CC). We investigated mucosal eosinophil and neutrophil granulocytes and T-cells involved in the inflammatory processes and aimed at determining whether these processes are reflected in the faecal (F) contents of specific proteins secreted by cells in the intestinal mucosa. LÄS MER

7. 5. Serological and faecal biomarkers in inflammatory bowel disease

   Författare :Karin Amcoff; Jonas Halfvarson; Marie Carlsson; Hans Törnblom; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn s disease; ulcerative colitis; inflammatory bowel disease; faecal calprotectin; antibodies; eosinophils; ECP; EDN;

   Sammanfattning : The inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are relapsing and remitting disorders characterised by chronic inflammation at various sites in the gastrointestinal tract, resulting in diarrhoea and abdominal pain. Neither the aetiology nor the pathophysiology is yet fully understood, and there is currently no cure. LÄS MER