Sökning: "E7 protein"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden E7 protein.

  1. 1. Novel Cutaneous Human Papillomaviruses and Biomarkers in the Skin Lesions

    Författare :Natasa Vasiljevic; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prevalence; E7 protein; Non-melanoma skin cancer; biomarkers; keratoachantoma; Human papillomavirus;

    Sammanfattning : Non-melanoma skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. LÄS MER

  3. 2. Monoclonal antibodies against human papillomavirus E7 oncoprotein for diagnosis of cervical neoplasia and cancer

    Författare :Maria Lidqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus HPV ; Cervical cancer; Cervical neoplasia; E7 oncoprotein; Monoclonal antibodies; Cytology; Immunocytochemistry; Phage display;

    Sammanfattning : Cervical cancer is the second most common cancer among women worldwide with half a million of new cases every year. Cervical cancer is caused by oncogenic human papillomaviruses (HPVs), with HPV16 and 18 being the most frequently detected types. LÄS MER

  4. 3. Regulation of HPV16 Early Gene Expression

    Författare :Yunji Zheng; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV16; splicing; mRNA; hnRNP A1; hnRNP G; E6; E7; E1; E2;

    Sammanfattning : Human papillomavirus type 16 (HPV16) is the most common high-risk type and isassociated with more than 50% cervical cancer cases as well as a number of headand neck cancer cases. The life cycle of HPV16 is strictly linked to celldifferentiation in the squamous epithelium with expression of the HPV16 earlygenes. LÄS MER

  5. 4. The antagonistic role of activated oncogenes and apoptosis : studies of n-myc and p53 in lymphoid tumorigenesis

    Författare :Yisong Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MPC; EmyN-myc transgene; J3D T Iymphoma cells; p53; v-m y cretrovirus; bcl-2; Gl cell cycle arrest; apoptosis; HPV 16 E7;

    Sammanfattning : Inactivation of the p53 tumor suppressor gene and activation of proto-oncogenes have been implicated in the initiation and/or progression of a number of neoplasms. In this thesis, the involvement of N-myc gene activation has been studied in mouse plasmacytomagenesis and the role of wild-type (wt)p53 and oncogene activation has been evaluated with particular emphasis on apoptosis. LÄS MER

  7. 5. The Regulation of Human Papillomavirus Type16 Early Gene Expression

    Författare :Xiaoxu Cui; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; splicing; hnRNP D; m6A; LCR;

    Sammanfattning : AbstractHuman papillomaviruses (HPVs) are small non enveloped viruses that contain a double-stranded circular DNA genome of approximately 8kb in size. It has been estimated that approximately 5% of all cancers are caused by HPV infection. Cervical cancer represents the majority of HPV-associated anogenital cancers worldwide. LÄS MER