Sökning: "Drug release"

Visar resultat 1 - 5 av 318 avhandlingar innehållade orden Drug release.

  1. 1. Microgels as drug delivery vehicles : loading and release of amphiphilic drugs

    Författare :Yassir Al-Tikriti; Per Hansson; Magnus Bergström; Matthew Libera; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microgel; amphiphilic drug; phase separation; micropipette; Raman microscopy; controlled release; drug delivery; SAXS; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : Polyelectrolyte microgels are used as delivery vehicles for amphiphilic drugs in, e.g., treatments of liver cancer by a method called trans-arterial chemoembolization. LÄS MER

  3. 2. Drug Eluting Hydrogels : Design, Synthesis and Evaluation

    Författare :Lage Ahrenstedt; Deon Bezuidenhout; Michael Malkoch; University of Cape Town; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drug delivery; PEGylation; Rapamycin; Dexamethasone; Controlled release; Hydrogels; Slow release;

    Sammanfattning : Hydrogels have successfully proved themselves useful for drug delivery applications and several delivery routes have been developed over the years. The particular interest in this work was to design, synthesise and evaluate in situ forming drug eluting hydrogels, which have the potential to ameliorate the healing of cardiovascular diseases. LÄS MER

  4. 3. Extended-release metoprolol : studies on the drug release and pharmacokinetics of a multiple-unit formulation

    Författare :Anders Sandberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  5. 4. Prolonged Drug Release from Gels, using Catanionic Mixtures

    Författare :Tobias Bramer; Katarina Edsman; Per Hansson; Stefan Ulvenlund; Uppsala universitet; []
    Nyckelord :Pharmaceutics; gel; catanionic; vesicle; micelle; controlled release; diffusion; surfactant; drug delivery; Galenisk farmaci;

    Sammanfattning : The use of catanionic drug-surfactant mixtures was proven to be an efficient novel method of obtaining prolonged drug release from gels. It was shown that various commonly used drug compounds are able to form catanionic mixtures together with oppositely charged surfactants. LÄS MER

  7. 5. Mesoporous magnesium carbonate as a drug delivery vehicle for stabilising amorphous drugs and regulating their release rate

    Författare :Peng Zhang; Maria Strømme; Niklas Hedin; Uppsala universitet; []
    Nyckelord :mesoporous; magnesium carbonate; drug delivery; solubility enhancement; bioavailability; pharmacokinetics; diffusion release; controlled release; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

    Sammanfattning : In today’s drug discovery, the number of candidate drugs based on new molecular entities with poor aqueous solubility is increasing. Since poor aqueous solubility of an active pharmaceutical ingredients (APIs) is associated with low bioavailability and thus limite their therapeutic effect, this is often a great challenge in the development of new drugs when oral administration is the preferred route of administration. LÄS MER