Sökning: "Dosage Compensation"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Dosage Compensation.

  1. 1. The Evolution of Sex Chromosomes and Dosage Compensation in Structurally Dynamic Butterfly Genomes

    Författare :Lars Höök; Niclas Backström; Elina Immonen; Beatriz Vicoso; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome evolution; Dosage compensation; Sex-biased gene expression; Faster-Z; Lepidoptera; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Dimorphic sex chromosomes have evolved independently throughout evolution from initially homologous autosomes. Recombination suppression between the sex chromosomes causes one sex chromosome to degenerate, which will influence evolution of sex-linked genes. LÄS MER

  3. 2. Chromosome-specific adaptations of RNA stability and the roles of the roX RNAs in dosage compensation

    Författare :Marie-Line Faucillion; Jan Larsson; Jean-Yves Roignant; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; dosage compensation; buffering; RNA stability; RNA decay; RNA half-life; RNA-seq; genome-wide; sex chromosomes; evolution; roX1; roX2; POF; MSL; molekylärbiologi; Molecular Biology;

    Sammanfattning : Sex chromosomes evolved from an ancient pair of autosomes and the Y chromosome lost most of its genetic information in the process. This created two kinds of genomic imbalances: the first one between males (XY) and females (XX) and the second one between the sex chromosomes and the autosomes (X:AA). LÄS MER

  4. 3. Genomic adaptation and gene-dosage regulation of Drosophila melanogaster cells, and long-read software developments

    Författare :Jacob Lewerentz; Per Stenberg; Jan Larsson; Bergman Casey; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; cell line; long read; Nanopore; Pacbio; Illumina; cancer; genome evolution; dosage compensation; structural variant; software; bioinformatics;

    Sammanfattning : Cells are the vehicles that allows genetic code to proliferate in the world, taking on various forms – as illustrated by the tree of life. The cell features are determined by the manufacturing of proteins, a process that has its blueprints encoded as genes in the genome. LÄS MER

  5. 4. On the Evolution of the Avian Transcriptome

    Författare :Severin Uebbing; Hans Ellegren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; evolution; gene expression; regulation; RNA-seq; transcriptomics; proteomics; sex chromosome; dosage compensation; divergence; ASE; birds; Ficedula; flycatcher; chicken; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Change in gene expression is a powerful tool for evolution, because seemingly small expression changes can contribute important steps towards adaptation without necessarily affecting the whole organism. There is still much to learn about how gene expression evolves on genome- and population-wide levels, especially in non-model organisms. LÄS MER

  7. 5. Genomic and Peptidomic Characterization of the Developing Avian Brain

    Författare :Birger Scholz; Lennart Dencker; Eric Vilain; Uppsala universitet; []
    Nyckelord :Toxicology; Sex differentation; Sex determination; Sex chromosomes; Dosage Compensation; Genetic; Chickens; Coturnix; Gene Expression Profiling; Neuropeptides; Diencephalon; Toxikologi;

    Sammanfattning : Chicken and Japanese quail are commonly used models in developmental and sex specific neuroendocrine research. There is relatively little known about the mechanisms behind their sex specific brain development, especially regarding the impact of the sex chromosomes (male: ZZ, female ZW) in relation to gonadal hormones. LÄS MER