Sökning: "Dominik Possner"

Hittade 1 avhandling innehållade orden Dominik Possner.

1. 1. Structural studies of glycoprotein sorting and processing complexes in the early secretory pathway

   Författare :Dominik Possner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The secretory pathway of a eukaryotic cell exerts a stringently regulated quality control system for the correct folding and transport of newly synthesised proteins and their subsequent transfer to their final destinations. While this pathway has been mostly studied in yeast, it has become increasingly clear that aberrations in its function are the main causes of a range of human disorders, and we are still in the process of gathering knowledge of the underlying molecular structures and mechanisms of the disease-causing agents in order to fully understand their impact. LÄS MER