Sökning: "Domain structure"
Visar resultat 6 - 10 av 847 avhandlingar innehållade orden Domain structure.
6. Structure-function relationships of the human Runx1 transcription factor
Sammanfattning : Runx transcription factors contain a DNA-binding andtransactivating α-subunit and a β-subunit (CBFβ)that serves to increase the DNA binding affinity of theα-subunit. The DNA binding domain of Runx proteins isnamed the Runt homology domain (RD) after its strong sequencehomology to theDrosophilaprotein Runt. LÄS MER
7. NMR STUDIES ON STRUCTURE AND DYNAMICS OF TWO-DOMAIN PROTEINS
Sammanfattning : The general objective of the present thesis work was to examine 3-dimensional structure as well as the motional properties of two different types of two-domain proteins by solution-state NMR. One of the major tasks of this thesis work was to investigate the domain orientation of these molecules by employing residual dipolar couplings (RDC) which can be used as orientational restraints for increasing the accuracy of protein structures determined by NMR. LÄS MER
8. Tunable Magnetic Properties of Transition Metal Compounds
Sammanfattning : The magnetic properties of transition metal compounds have been studied using SQUID-magnetometry, magnetic force microscopy and Lorentz transmission electron microscopy. New magnetic materials have been found and their magnetic properties have been determined. How the magnetic properties of a material can be changed through e.g. LÄS MER
9. Vitamin K-dependent protein S - studies of synthesis, structure and function
Sammanfattning : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. LÄS MER
10. Finite Element Modelling of Fluid-Structure Interaction
Sammanfattning : The dynamic interaction between non-viscid, compressible fluid and an elastic structure is studied. Finte element formulations, using the weighted residual method, are derived. Different primary variables in the fluid domain are used and different source functions are considered. LÄS MER