Sökning: "DHFR-TS"

Hittade 2 avhandlingar innehållade ordet DHFR-TS.

1. 1. Avian Malaria and Related Blood Parasites: Molecular Diversity, Ecology and Evolution

   Författare :Olof Hellgren; MEMEG; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diversity; Plasmodium; bird-migration; transmission; blackfly; host-specificity; host-preference; cytochrome b; DHFR-TS; recombination; phylogeny; Ecology; Ekologi; Genetics; cytogenetics; Genetik; cytogenetik; Parasitology human and animal ; Haemoproteus; Leucocytozoon; Parasitologi människa och djur ; Animal ecology; Djurekologi; Natural science; Naturvetenskap;

   Sammanfattning : Malaria-like parasites consist of a large group of species that infects primates, rodents, bats, lizard and birds. I have focused on parasites from the genera Haemoproteus, Plasmodium and Leucocytozoon that are infecting birds. LÄS MER

3. 2. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification

   Författare :Elisabet Vikeved; UCM Alsmark; Christian Sköld; David Horn; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leishmaniasis; Drug discovery; Lateral gene transfer; Comparative genomics; Virtual screening; Target fishing; Marine natural products;

   Sammanfattning : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. LÄS MER