Sökning: "CsA"

Visar resultat 1 - 5 av 63 avhandlingar innehållade ordet CsA.

  1. 1. Islet xenotransplantation : An immunological study in the pig-to-mouse model

    Författare :Birgitta Benda; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; xenotransplantation; porcine; islet; in vivo; knock-out mouse; immunohistochemistry; CsA; MDL 201; 449A; Ig; FcR; IL-6; perforin; granzyme B; macrophage; eosinophilic granulocyte; T cell; TCR; IFN- g; TNF- a; IL-2; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

    Sammanfattning : Successful clinical xenotransplantation, i.e., transplantation between species, would eliminate the shortage of donor organs. In order to study the acute cellular rejection reaction following discordant xenogeneic transplantation, an experimental pig-to- mouse islet xenotransplantation model was established. LÄS MER

  3. 2. Det sociala kriget och kapitalets ansvar : Social ingenjörskonst mellan affärsintresse och samhällsreform i USA och Sverige 1899-1914

    Författare :David Östlund; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; social ingenjörskonst; den sociala frågan; arbete och kapital; arbetsmarknadsrelationer; paternalism; välfärdskapitalism; effektivitet; arbetsmiljö; arbetarskydd; social anpassning; ömsesidighet; W.H. Tolman; Centralförbundet för socialt arbete; CSA; den svenska modellen; History of science and ideas; Idé- o lärdomshistoria;

    Sammanfattning : .... LÄS MER

  4. 3. Cyclosporin A-induced gingival overgrowth in renal transplant patients : a clinical, histological and experimental study

    Författare :Biniyam Wondimu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cyclosporin A gingival overgrowth gingival fibroblasts nephrotoxicity renal transplant saliva;

    Sammanfattning : Cyclosporine A (CsA) is widely used as an effective immunosuppressive agent to prevent rejection of organ transplants, as well as in the treatment of patients with various autoimmune diseases. The clinical use of CsA, however, is associated with adverse side effects, including nephrotoxicity, hepatotoxicity, hypertension, and neurotoxicity as well as gingival overgrowth. LÄS MER

  5. 4. Childhood Sexual Abuse Against Girls in Sub-Saharan Africa : Individual and Contextual Risk Factors

    Författare :Ismail Yahaya; Gloria Macassa; Joaquim Soares; Antonio Ponce De Leon; Antony Beech; Mittuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol; child sexual abuse; demographic and health survey; multilevel; neighbourhood; sexual violence; smoking; social disorganisation; socio-economic status; sub-Saharan Africa;

    Sammanfattning : Background and objectives: Childhood sexual abuse (CSA) is a substantial public health and human rights problem, as well as a growing concern in sub-Saharan Africa (SSA). It has both short and long term effects on girls: physical and psychological, including negative sexual outcomes. LÄS MER

  7. 5. Mitochondrial permeability transition following calcium overload. - Its role in neuronal cell death and potential as a pharmacological target

    Författare :Magnus Hansson; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; farmakognosi; farmaci; Bioenergetik; Bioenergetics; neuropsykologi; toxikologi; neurofysiologi; Neurologi; Neurology; neurophysiology; neuropsychology; Neurodegeneration; Mitochondria; Brain; Pharmacological sciences; pharmacognosy; pharmacy; Farmakologi; toxicology;

    Sammanfattning : There is currently no clinically available drug with neuroprotective properties to limit the evolving cell death following e.g. stroke or traumatic brain injury. The mitochondrial permeability transition (mPT) is a potential pathological mechanism causing cell death in the CNS. LÄS MER