Sökning: "Collateral sprouting"

Hittade 5 avhandlingar innehållade orden Collateral sprouting.

  1. 1. End-to-side nerve repair - A study in the forelimb of the rat

    Författare :Eleana Bontioti; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nerve regeneration; Kirurgi; traumatology; Surgery; orthopaedics; Medicin människa och djur ; Medicine human and vertebrates ; Retrograde labelling; ATF3; Collateral sprouting; ortopedi; traumatologi; Nerve injury;

    Sammanfattning : Nerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. LÄS MER

  3. 2. Collateral development in limb ischemia : aspects of endogenous and stimulated arteriogenesis

    Författare :Ulrika Palmer Kazen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PAD; CLI; intermittent claudication; VEGF; FGF-2; angiogenesis; arteriogenesis; gene therapy; adenovirus; AdFGF-4; rat hindlimb ischemia model; randomized clinical trial;

    Sammanfattning : Peripheral arterial disease (PAD) is common among elderly and affects about 20% of the population above the age of 60 years. PAD is a strong marker for future cardiovascular events and increased mortality due to widespread atherosclerotic lesions in the coronary and cerebral arteries. LÄS MER

  4. 3. Peptidergic innervation of periarticular tissue : a study in the rat

    Författare :Paul Ackermann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunohistochemistry; radioimmunoassay; pain measurement; Achilles tendon; collateral ligaments; joint capsules; tendon rupture; regeneration; peripheral nervous system; neuropeptides; delta opioid receptor;

    Sammanfattning : Painful musculo-skeletal disorders pose a tremendous burden on the healthcare system, the main reason being the limited knowledge of the underlying pathomechanisms and lack of specific treatment. Hypothetically, the peripheral nervous system in the musculo-skeletal tissues plays an important role in the regulation of pain, inflammation, vasoactivity and also tissue repair. LÄS MER

  5. 4. Repair of divided peripheral nerves : experimental studies in rabbit and rat

    Författare :Barbara Lutz; Pietro Giovanoli; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The general aim of this thesis was to provide new knowledge, through experimental studies, that may contribute to an improvement of the results after microsurgical peripheral nerve repair in patients.An adequate function of the human body depends, among other things, on a correctly functioning peripheral nervous system. LÄS MER

  7. 5. Experimental spinal cord injury : methodological and neuroimmunological contributions with some historical background

    Författare :Matthew Joseph Fraidakis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Spinal cord injury (SCI) is an incurable neurotraumatic catastrophe that afflicts mostly young individuals with resultant functional impairment of varying degrees of severity. The single pharmacologic treatment option at present is systemic methylprednisolone administration within 8 hours postinjury oftentimes accompanied by neurosurgical interventions. LÄS MER