Sökning: "Codon usage bias"

Hittade 4 avhandlingar innehållade orden Codon usage bias.

  1. 1. Biased Evolution : Causes and Consequences

    Författare :Gerrit Brandis; Diarmaid Hughes; Erik Böttger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Codon usage bias; Post-transcriptional regulation; Recombination; Inversion; EF-Tu; Frameshift suppression; Antibiotic resistance; Rifampicin; Ciprofloxacin; Compensatory evolution; Drug efflux; RNA polymerase; DNA gyrase; Mikrobiologi; Microbiology;

    Sammanfattning : In evolution alternative genetic trajectories can potentially lead to similar phenotypic outcomes. However, certain trajectories are preferred over others. These preferences bias the genomes of living organisms and the underlying processes can be observed in ongoing evolution. LÄS MER

  3. 2. Evolution of symbiotic lineages and the origin of new traits

    Författare :Daniel Tamarit; Siv G. E. Andersson; Lisa Klasson; Amparo Latorre; Julian Parkhill; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; symbiosis; host-association; Lactobacillus; Bifidobacterium; Rhizobiales; Bartonella; honeybees; ants; codon usage bias; genome architecture; genome organization; gene transfer agent; evolutionary genomics; comparative genomics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. LÄS MER

  4. 3. Translational regulation in Plasmodium falciparum

    Författare :Sherwin Chan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasmodium falciparum is the causative agent of the most malignant form of human malaria, which remains as one of the most devastating infectious diseases. In face of a continuous international effort to eliminate the disease, the parasite not only has evaded a total obliteration, but has now evolved resistance to many of the available drugs. LÄS MER

  5. 4. Machine learning and data-parallel processing for viral metagenomics

    Författare :Zurab Bzhalava; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : More than 2 million cancer cases around the world each year are caused by viruses. In addition, there are epidemiological indications that other cancer-associated viruses may also exist. However, the identification of highly divergent and yet unknown viruses in human biospecimens is one of the biggest challenges in bio- informatics. LÄS MER