Sökning: "Codon Usage"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Codon Usage.

  1. 1. Genome Evolution of Neurospora tetrasperma

    Författare :Yu Sun; Hanna Johannesson; Siv Andersson; Toni Gabaldon; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neurospora tetrasperma; next-generation sequencing; introgression; intron; chromosomal inversion; codon usage; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : In this thesis work, I have used a comparative genomics approach to study a fungal model organism, Neurospora tetrasperma. My specific focus has been on genomic introgression, intron evolution, chromosomal structural rearrangements and codon usage. LÄS MER

  2. 2. Posttranscriptional Regulation of Human Papillomavirus Type 16 Late mRNAs

    Författare :Brian Collier; Carl Baker; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV 16; Negative Element; Translation; mRNA stability; Codon Usage; RNA binding proteins; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : The lifecycle of the human papillomavirus (HPV) is strictly linked to the programmed differentiation of the host cell it infects. Production of late proteins, which are used for the production of the major and minor capsid proteins, is only seen upon terminal differentiation of the epithelium. LÄS MER

  3. 3. The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression

    Författare :Daniel Öberg; Stefan Schwartz; Sheila Graham; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; HPV-16; polyadenylation; mRNA stability; codon usage; hnRNP H; DSE; splicing; negative element; RNA processing; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : High-risk type human papillomaviruses (HPVs) are associated with cancer. HPVs are strictly epitheliotropic and infect basal cell layers, establishing a life cycle strongly linked to the differentiation stage of the infected cells. The viral capsid late genes, L2 and L1, are only expressed in terminally differentiated epithelium. LÄS MER

  4. 4. Biased Evolution : Causes and Consequences

    Författare :Gerrit Brandis; Diarmaid Hughes; Erik Böttger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Codon usage bias; Post-transcriptional regulation; Recombination; Inversion; EF-Tu; Frameshift suppression; Antibiotic resistance; Rifampicin; Ciprofloxacin; Compensatory evolution; Drug efflux; RNA polymerase; DNA gyrase; Mikrobiologi; Microbiology;

    Sammanfattning : In evolution alternative genetic trajectories can potentially lead to similar phenotypic outcomes. However, certain trajectories are preferred over others. These preferences bias the genomes of living organisms and the underlying processes can be observed in ongoing evolution. LÄS MER

  5. 5. Evolution of symbiotic lineages and the origin of new traits

    Författare :Daniel Tamarit; Siv G. E. Andersson; Lisa Klasson; Amparo Latorre; Julian Parkhill; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; symbiosis; host-association; Lactobacillus; Bifidobacterium; Rhizobiales; Bartonella; honeybees; ants; codon usage bias; genome architecture; genome organization; gene transfer agent; evolutionary genomics; comparative genomics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. LÄS MER