Sökning: "Co III complex"

Visar resultat 1 - 5 av 225 avhandlingar innehållade orden Co III complex.

1. 1. Complex causality : Bridging analytical sociology and social-ecological systems research

   Författare :Rodrigo Martínez Peña; Petri Ylikoski; Maja Schlüter; Karl Wennberg; Carl Nordlund; Edmund Chattoe-Brown; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Causal reasoning; Mechanism-based theorizing; Sustainability; Interdisciplinarity;

   Sammanfattning : Understanding the complexity of social-ecological phenomena like climate change, ocean acidification, and biodiversity loss requires interdisciplinary collaboration. However, scholars that engage in interdisciplinary work face the challenge of grasping other disciplines’ causal reasoning. LÄS MER

3. 2. Pain and health in adolescents and young adults – pieces of a puzzle

   Författare :Julia Söderström Malmborg; Ann Bremander; Stefan Bergman; M. Charlotte Olsson; Elin Ekblom Bak; Högskolan i Halmstad; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; musculoskeletal pain; health status; physical activity; orthorexia nervosa; sports; sleep; stress; anxiety; depression; physical maturity; students; school; biopsychosocial;

   Sammanfattning : Background: Musculoskeletal pain is a burden for the individual and for society, and it has a negative impact on overall health. The biological, psychological, and social factors that govern pain and health form a complex puzzle to put together. LÄS MER

4. 3. Understanding the genetic basis of complex traits

   Författare :Yanjun Zan; Örjan Carlborg; Pär Ingvarsson; Uppsala universitet; []
   Nyckelord :genetic architecture; complex traits; epistasis; multi-allelic; genotype by environment interaction; polygenic adaptation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : Recent advances in genetics and genomics have provided numerous opportunities to study the genetic basis of complex traits. Nevertheless, dissecting the genetic basis of complex traits is still challenged by the complex genetic architecture, in which many genes are involved, and many have small contributions to phenotypic variation, interactions with other genes or environmental factors. LÄS MER

5. 4. Patterns in big data bioinformatics : Understanding complex diseases with interpretable machine learning

   Författare :Mateusz Garbulowski; Jan Komorowski; Ryan J. Urbanowicz; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; complex diseases; big data; machine learning; transcriptomics; life sciences; rough sets; Bioinformatics; Bioinformatik;

   Sammanfattning : Alterations in the flow of genetic information may lead to complex diseases. Such changes are measured with various omics techniques that usually produce the so-called “big data”. Using interpretable machine learning (ML), we retrieved patterns from transcriptomics data sets. LÄS MER

7. 5. Uncovering biomarkers and molecular heterogeneity of complex diseases : Utilizing the power of Data Science

   Författare :Sara Younes; Linda Holmfeldt; Jan Komoroski; Aedin Culhane; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complex Disease; Cancer; Autoimmune diseases; Acute Myeloid Leukemia; Systemic Lupus Erythematosus; Bioinformatics; Machine Learning; Data Science; Statistical Analysis; Bioinformatics; Bioinformatik; Computer Science; Datavetenskap;

   Sammanfattning : Uncovering causal drivers of complex diseases is yet a difficult challenge. Unlike single-gene disorders complex diseases are heterogeneous and are caused by a combination of genetic, environmental, and lifestyle factors which complicates the identification of patient subgroups and the disease causal drivers. LÄS MER