Sökning: "Cell and Organism Biology"

Visar resultat 1 - 5 av 246 avhandlingar innehållade orden Cell and Organism Biology.

  1. 1. Systems Biology of Yeast Lipid Metabolism

    Detta är en avhandling från Chalmers University of Technology

    Författare :Pramote Chumnanpuen; Chalmers tekniska högskola.; Chalmers University of Technology.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cellbiologi; Cell biology; Genetik; Genetics; Molekylärbiologi; Molecular biology; Bioinformatik; Bioinformatics; Analytisk kemi; Analytical chemistry; Yeast lipid metabolism; Integrated analysis; Inositol-choline; Snf1; TORC1; Ino2; Ino4; Opi1; high throughput techniques; Transcriptome; Lipidome.;

    Sammanfattning : Lipid metabolism plays an important role in the development of many different life-style related diseases, such as type 2 diabetes and atherosclerosis, and understanding the molecular mechanisms behind regulation of lipid biosynthesis and degradation may lead to development of new therapies. In this project we undertook a global study of lipid metabolism in the eukaryotic model organism Saccharomyces cerevisiae. LÄS MER

  2. 2. Heterogeneity of human metabolism in health and disease: a modelling perspective

    Detta är en avhandling från Chalmers University of Technology

    Författare :Pouyan Ghaffari Nouran; Chalmers tekniska högskola.; Chalmers University of Technology.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fatty acid metabolism; heterogeneity; gut microbiome; amino acids metabolism; genome-scale metabolic models; community modeling; cancer metabolism; lung cancer;

    Sammanfattning : Metabolism is broadly defined as the sum of biochemical reactions within cells that are involved in maintaining the living state of the organism. Profound importance of metabolism comes from the fact that it is the sole source of energy that allows life to resist to be degraded into entropy. LÄS MER

  3. 3. Adenosine Receptors and Regulation of Rabbit Lacrimal Gland Secretion

    Detta är en avhandling från Chalmers University of Technology

    Författare :Maria Edman; Högskolan i Kalmar.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellbiology; Ophalthalmology; Lacrimal Gland; Cellbiologi; Oftalmologi; Tårkörtel; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Cell and Organism Biology; Cell- och organismbiologi;

    Sammanfattning : .... LÄS MER

  4. 4. Investigating Amyloid β toxicity in Drosophila melanogaster

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Maria Jonson; Linköpings universitet.; Linköpings universitet.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In this thesis Drosophila melanogaster (the fruit fly) has been used as a model organism to study the aggregation and toxic properties of the human amyloid β (Aβ) peptide involved in the onset of Alzheimer's disease (AD). AD is one of many misfolding diseases where the important event of a protein to adopt its’ specific three-dimensional structure has failed, leading to aggregation and formation of characteristic amyloid fibrils. LÄS MER

  5. 5. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Ufuk Kirik; Lunds universitet.; Lund University.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cancer; proteome profiling; bioinformatics; pathway analysis; mass spectrometry; Quantitative proteomics;

    Sammanfattning : Popular Abstract in Swedish Den mänskliga kroppen är ett komplext maskineri med en rad olika reglersystem och kontrollmekanismer. Flera grenar av modern biomedicinsk forskning riktar sig mot olika nivåer av detta komplexa maskineri. LÄS MER