Sökning: "Cecilia Wadell"

Hittade 1 avhandling innehållade orden Cecilia Wadell.

1. 1. Nasal Drug Delivery : In Vitro Studies on Factors Influencing Permeability and Implications on Absorption

   Författare :Cecilia Wadell; Frans Merkus; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

   Sammanfattning : Nasal delivery is a feasible alternative to oral or parenteral administration for some drugs because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. The main objective of this thesis was to investigate factors influencing the permeability of the nasal mucosa to various compounds and to evaluate implications for drug absorption via the nasal route. LÄS MER