Sökning: "Cecilia Annerén"

Hittade 2 avhandlingar innehållade orden Cecilia Annerén.

  1. 1. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

    Författare :Cecilia Annerén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. LÄS MER

  3. 2. Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells

    Författare :Sara Pijuan Galitó; Cecilia Annerén; Lena Kjellén; Christopher Ward; Uppsala universitet; []
    Nyckelord :Pluripotent stem cells; Inter-alpha inhibitor; culture method; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while maintaining their capacity to differentiate into any cell type of an organism, thus offering novel sources for drug screening, in vitro disease modelling, and cell replacement therapies. However, due to their sensitive nature, many PSC lines are still cultured using undefined components such as serum or serum-derived components, on either feeder cells or complex protein mixes such as Matrigel or gelatine. LÄS MER