Sökning: "Cartilage markers"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden Cartilage markers.
1. Molecular and clinical studies of cartilage and bone macromolecules in arthritis
Sammanfattning : The pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. LÄS MER
2. Developing knee joint osteoarthritis: Clinical, radiographical and biochemical features
Sammanfattning : The aim of this project was to study clinical, radiographical and biochemical features of developing, symptomatic knee osteoarthritis (OA) prospectively in individuals aged 35-54 from the general population. A questionnaire to a random sample of 2 000 individuals in the district of Laholm, Sweden, identified 279 individuals (15% of the population) with chronic (>3 months) knee pain. LÄS MER
3. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation
Sammanfattning : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. LÄS MER
4. Cartilage Tissue Engineering; the search for chondrogenic progenitor cells and associated signalling pathways
Sammanfattning : The socioeconomic cost of articular cartilage related diseases in the Western world is very high. The suffering of the individual patient is even more problematic. LÄS MER
5. Joint disease biomarkers - discovery and application
Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER