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1. 1. Genomic and Molecular Aspects of Mature Human B Cells

   Författare :Carl-Magnus Högerkorp; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Human; B-cell; Germinal center; Centroblast; serology; Immunology; onkologi; cancer; Cytologi; cancerology; oncology; Microarray; Cytology; Mantel cell lymphoma; Immunologi; serologi; Centrocyte;

   Sammanfattning : This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma cells, is not only of importance for the curious scientist, but will also benefit the understanding of B cells in disease. LÄS MER