Sökning: "Cardiopulmonary bypass"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden Cardiopulmonary bypass.

1. 1. Heparin coating and cardiotomy suction in cardiopulmonary bypass

   Författare :Staffan Svenmarker; Torkel Åberg; Gunnar Engström; Thomas Karlsson; Jarle Vaage; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; cardiopulmonary bypass; oxygenators; heparin; S100 proteins; blood loss; haemostasis; memory; outcome and process assessment; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

   Sammanfattning : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). LÄS MER

3. 2. Cardiopulmonary bypass: Clinical studies in cardiac surgery patients

   Författare :Mikael Barbu; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiopulmonary bypass; Cardiac surgery; Colloid; Prime; Acute kidney injury; Brain injury marker; Hemostasis;

   Sammanfattning : BACKGROUND: Cardiopulmonary bypass (CPB) is necessary to facilitate most cardiac operations. Although the vast majority of patients tolerate CPB physiology in conjunction with cardiac surgery well, there is risks of adverse outcomes. Optimal CPB perfusion is not defined, and may vary according to operation and patient specific factors. LÄS MER

4. 3. Cerebral Perfusion during Cardiopulmonary Bypass

   Författare :Thomas Tovedal; Fredrik Lennmyr; Stefan Thelin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Impaired superior vena cava (SVC) cannula outflow during cardiopulmonary bypass (CPB) is a frequent issue, often manifested by only marginal changes in routine monitoring parameters. Nevertheless, significant impact on cerebral perfusion may result. LÄS MER

5. 4. Cardiopulmonary bypass and the kidney - studies on patients undergoing cardiac surgery

   Författare :Lukas Lannemyr; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiac surgery; cardiopulmonary bypass; glomerular filtration rate; renal blood flow; renal oxygenation; tubular injury; N-acetyl-ß-D-glucoseaminidase;

   Sammanfattning : Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), and has a major impact on morbidity, mortality and costs. The mechanism of CPB-related renal impairment is not fully understood. LÄS MER

7. 5. Atelectasis and gas exchange impairment after cardiopulmonary bypass : An experimental study

   Författare :Lennart Magnusson; Uppsala universitet; []
   Nyckelord :Medical sciences; Lung: cardiopulmonary bypass; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

   Sammanfattning : Despite of the improvement in management and equipment for cardiopulmonary bypass (CPB), postoperative pulmonary complications remain a major problem after cardiac surgery. In the present thesis, using a pig model, atelectasis has been tested as a cause of the increase in intrapulmonary shunt commonly seen after CPB. LÄS MER