Sökning: "Candida albicans."

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Candida albicans..

  1. 1. Interaction Studies of Secreted Aspartic Proteases (Saps) from Candida albicans Application for Drug Discovery

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Dan Backman; Uppsala universitet.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; SPR Biosensor; Secreted aspartic proteases; Candida albicans; interaction kinetics; drug discovery; protease inhibitor; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Sammanfattning : This thesis is focused on enzymatic studies of the secreted aspartic proteases (Saps) from Candida albicans as a tool for discovery of anti-candida drugs. C. albicans causes infections in a number of different locations, which differ widely in the protein substrates available and pH. Since C. LÄS MER

  2. 2. In vitro Pharmacodynamics of Antifungal Agents in the Treatment of Candida Infections

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anders Lignell; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amphotericin B; antagonism; Candida; human serum; inhibition; interaction; in vitro; kinetic model; pharmacodynamics; pharmacokinetics; posaconazole; protein binding; voriconazole; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Pharmacodynamic studies are important for the optimal use of antimicrobial agents. Combination antifungal therapy may be one method to improve outcome in invasive Candida infections. LÄS MER

  3. 3. Development and validation of a localized murine candidiasis model : The pathogenesis, chemotheraphy and defense mechanisms to Candida mastitis in the lactating mouse

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Faisal Abdi Guhad; Uppsala universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Murine model; Candida albicans; Pathogenesis; Virulence factors; Amphotericin B; Fluconazole; Complement activation; C3c; SCID mice; Nude mice; Fysiologi och anatomi; MEDICINE Physiology and pharmacology; MEDICIN Fysiologi och farmakologi; fysiologi; Physiology;

    Sammanfattning : A murine model of localized candidiasis (mastitis) was developed. The model was analyzed withrespect to its discriminative abilities through investigation of the virulence properties of C.albicans mutant strains compared with the wild-type parental strain. LÄS MER

  4. 4. Genome dynamics and virulence in the human pathogen Candida glabrata

    Detta är en avhandling från Department of Biology, Lund University

    Författare :Khadija Mohamed Ahmad; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida glabrata; Pathogenic yeast; small chromosomes; Genome rearrangement; Haploid and diploid yeast; RNA interference.;

    Sammanfattning : Although the yeast Candida glabrata is considered to be a part of the commensal microflora in healthy individuals, during the last years it has been frequently isolated from patients with mucosal and systemic fungal infections. Now it is considered as the second most frequently isolated pathogenic yeast after Candida albicans. Despite its name, C. LÄS MER

  5. 5. Pharmaceutical And Immunollogical Challenge Of Fungal Pathogens

    Detta är en avhandling från Umeå Universitet

    Författare :Marios Stylianou; Umeå universitet.; Umeå universitet.; Umeå universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mast cells; Candida albicans; yeast to hyphal form; antifungal drugs; repurposed drugs; HTS;

    Sammanfattning : Incidences of fungal infections are on the rise in immunosuppressed people. Predominant causative agents for these mycoses are species of the genus Candida, including Candida albicans, Candida glabrata and Candida dublieniensis. Despite a wide range of emerging pathogens, C. albicans remains the leading cause. LÄS MER