Sökning: "C2-symmetric"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet C2-symmetric.

  1. 1. Microwave-Assisted Synthesis of C2-Symmetric HIV-1 Protease Inhibitors : Development and Applications of In Situ Carbonylations and other Palladium(0)-Catalyzed Reactions

    Författare :Johan Wannberg; Anders Hallberg; David C. Rees; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; HIV; protease inhibitors; palladium; carbonylations; molybdenum hexacarbonyl; dihydropyrimidone; DHPM; microwave; cross-coupling; diazylhydrazines; carbon monoxide; synthesis; C2-symmetric; HIV-1 protease inhibitors; aminocarbonylation; fluorous; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : The HIV protease is an essential enzyme for HIV replication and constitutes an important target in the treatment of HIV/AIDS. Efficient combination therapies using inhibitors of the reverse transcriptase and protease enzymes have led many to reevaluate HIV infections from a terminal condition to a chronic-but-manageable disease in the developed world. LÄS MER

  3. 2. Asymmetric synthesis via C2-symmetric aziridines

    Författare :Carin Birgersson; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 3. Synthesis and applications of C2-symmetric bis(aziridines) in asymmetric synthesis

    Författare :Adrian Harden; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  5. 4. Synthesis and Applications of C2-Symmetric Bis (Aziridines) in Asymmetric Synthesis

    Författare :Adrian Harden; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Models of NADH with C2 and D2 Symmetry

    Författare :Klas Skog; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A novel supramolecular approach to the design of NADH models is presented in this dissertation. The models can be divided into two types, C2 symmetric and D2 symmetric macrocyclic structures. The C2 symmetric models are made from a chiral C2 symmetric unit, two dihydronicotinamide units and a phenylene spacer, to form a macrocyclic structure. LÄS MER