Sökning: "Biologi med inriktning mot molekylär immunologi"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Biologi med inriktning mot molekylär immunologi.
1. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis
Sammanfattning : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. LÄS MER
2. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification
Sammanfattning : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. LÄS MER
3. Proximity Ligation Assay for High Performance Protein Analysis in Medicine
Sammanfattning : High quality reagents are preconditions for high performance protein analyses. But despite progress in some techniques, e.g. mass spectrometry, there is still a lack of affinity-based detection techniques with enhanced precision, specificity, and sensitivity. LÄS MER
4. Solid-phase Proximity Ligation Assays : High-performance and multiplex protein analyses
Sammanfattning : Protein biomarkers circulating in blood hold the promise of improved diagnosis, prognosis and follow-up of treatment of disease via minimally invasive procedures. For the discovery and validation of such biomarkers, methods are needed that can facilitate parallel, highly specific and in-depth analysis of the blood proteome. LÄS MER
5. DNA-Assisted Immunoassays for High-Performance Protein Analyses
Sammanfattning : Proteins play important roles in most cellular functions, such as, replication, transcription regulation, signal transduction, for catalyzing chemical reaction, etc. Technologies developed to identify proteins rely either on observing their own properties such as charge, size, mass to charge ratio or sequence composition; or on using affinity reagents that recognize specific protein targets. LÄS MER