Sökning: "Aromatic amino acids"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Aromatic amino acids.

1. 1. Synthesis of aromatic bis- and tris(amino acids) and chiral dendrimers

   Författare :Andreas Ritzén; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; HWE reaction; asymmetric hydrogenation; Heck reaction; Amino acids; chiral dendrimers;

   Sammanfattning : A number of protected aromatic bis- and tris(amino acids) have been synthesised by catalytic asymmetric hydrogenation of the corresponding didehydroamino acid derivatives. The didehydroamino acid derivatives were prepared either by a Heck coupling of a 2-amidoacrylate with an aryl dihalide, or by Horner-Wadsworth-Emmons olefination of aromatic aldehydes with phosphonylglycine reagents. LÄS MER

3. 2. Non Natural Aromatic Amino Acids Applications in cage-construction, metal ion coordination and asymmetric catalysis

   Författare :Ruxandra Ionescu; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diethylzinc additions.; spectroscopy; metal ion coordination; cage-like compounds; Amino acids; C3-symmetry; Organic chemistry; Organisk kemi;

   Sammanfattning : Aromatic non-natural amino acids, the outstanding feature of which was the presence of several arms, were synthesised and their properties investigated. The amino acids were synthesised following a standard procedure starting with a Horner-Wadsworth-Emmons or a Heck reaction, which provided didehydroamino acids. LÄS MER

4. 3. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods

   Författare :Javier Zurita; Leopold Ilag; Ulrika Nilsson; Margareta Törnqvist; Natalia Tretyakova; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amino acids; LC MS; fixed-charge derivatization; BMAA; chiral separation; pheromones; arctic aerosols; serum albumin adducts; benzo[a]pyrene diol epoxides; high-resolution MS; Analytical Chemistry; analytisk kemi;

   Sammanfattning : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). LÄS MER

5. 4. Synthesis of Non-Natural Aromatic Amino Acids Derivatives Solvent-free reactions-Versatile building blocks-Galectin inhibitors

   Författare :Erik Tullberg; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Naturvetenskap; Natural science; Multivalent galectin inhibitors; Multifunctional molecules; Amino Acids; Solvent-free reactions;

   Sammanfattning : This thesis deals with three topics concerning the synthesis of non-natural also known as unnatural amino acid derivatives. In the first, solvent-free reaction conditions for the Heck reaction were developed that were superior to previous conditions because the reaction time could be reduced and the work-up procedure simplified. LÄS MER

7. 5. Mass Spectrometry of Biologically Active Small Molecules : Focusing on polyphenols, alkaloids and amino acids

   Författare :Zdeněk Spáčil; Leopold L. Ilag; Frantisek Turecek; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; LC-MS; LDI; Mass spectrometry; HPLC; UHPLC; polyphenols; phenolic acids; BMAA; Separation methods; Separationsmetoder; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Sammanfattning : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. LÄS MER