Sökning: "ApoB100"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet ApoB100.

  1. 1. Regulatory Immune Responses and Repair Mechanisms in Atherosclerosis

    Författare :Sara Rattik; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Cardiovascular disease; T helper 2 cells; ApoB100; Regulatory B cells; Regulatory T cells; Smooth muscle cells; IL-22.;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. LÄS MER

  3. 2. Innate immune modulation in atherosclerosis : with focus on ApoB100 derived danger associated signal 1 (ApoBDS-1)

    Författare :Yajuan Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Elevated level of LDL is the most important risk factor for atherosclerosis. ApoB100 is the only unexchangeable protein in LDL particle. Recent reports have shown that native peptides of ApoB100 trigger activation of adaptive immune responses. Whether ApoB100 can activate innate immune response is unknown. LÄS MER

  4. 3. Cellular immune responses to low density lipoprotein in atherosclerosis

    Författare :Andreas Hermansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is an inflammatory disease of the medium and large sized arterial vessels. Low density lipoprotein (LDL) particles carrying cholesterol are trapped within the arterial intima and elicit both innate as well as adaptive immune responses. LÄS MER

  5. 4. Atherogenic lipoproteins and their interaction with proteoglycans

    Författare :Christofer Flood; Göteborgs universitet; []
    Nyckelord :apolipoprotein B; atherosclerosis; LDL; proteoglycan; sPLA2; ; retention;

    Sammanfattning : Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is the initiating event in atherogenesis. LÄS MER

  7. 5. Retention of atherogenic lipoproteins in atherogenesis

    Författare :Maria Gustafsson; Göteborgs universitet; []
    Nyckelord :apolipoprotein B; atherosclerosis; LDL; LpL; proteoglycans; retention; sPLA2;

    Sammanfattning : Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. LÄS MER