Sökning: "Antimicrobial resistance"

Visar resultat 1 - 5 av 110 avhandlingar innehållade orden Antimicrobial resistance.

  1. 1. Bacterial Resistance to Antimicrobial Peptides Rates, Mechanisms and Fitness Effects

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maria Pränting; Uppsala universitet.; [2010]
    Nyckelord :antimicrobial peptides; antibiotic resistance; fitness cost; bacterial evolution; small colony variants; cyclotides; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Mikrobiologi; Microbiology;

    Sammanfattning : The rapid emergence of bacterial resistance to antibiotics has necessitated the development of alternative treatment strategies. Antimicrobial peptides (AMPs) are important immune system components that kill microbes rapidly and have broad activity-spectra, making them promising leads for new pharmaceuticals. LÄS MER

  2. 2. Antimicrobial peptides in the treatment of infectious and inflammatory conditions Preclinical studies of mechanism of action, efficacy, and safety

    Detta är en avhandling från Göteborgs universitet

    Författare :Camilla Björn; RISE.; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides;

    Sammanfattning : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. LÄS MER

  3. 3. Aspects of Bacterial Resistance to Silver

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Susanne Sütterlin; Uppsala universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial resistance; Silver resistance; Klinisk bakteriologi; Clinical Bacteriology;

    Sammanfattning : Bacterial resistance to antibiotics has increased rapidly within recent years, and it has become a serious threat to public health. Infections caused by multi-drug resistant bacteria entail higher morbidity, mortality, and a burden to health care systems. LÄS MER

  4. 4. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Hava Lofton Tomenius; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

    Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER

  5. 5. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    Detta är en avhandling från Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Författare :Miriam Geörg; Stockholms universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). LÄS MER