Sökning: "Annelie Tjernlund"

Hittade 1 avhandling innehållade orden Annelie Tjernlund.

1. 1. Leukemia inhibitor factor (LIF) and gp130 in early defence against HIV-1 infection

   Författare :Annelie Tjernlund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :LIF; HIV-1; lymphoid tissue; cytokine; innate immune response; Jak Stat signalling pathway; cMAGI cells; siRNA;

   Sammanfattning : Leukemia inhibitor factor (LIF) is a polyfunctional cytokine that belongs to the IL-6 family which mainly signals through the Jak/Stat pathway via the gp130/LIFR-α heterodimer. The focus of my research has been to investigate and understand if and how LIF exerts HIV1 suppressing activity. LÄS MER