Sökning: "Anna Kim"

Hittade 4 avhandlingar innehållade orden Anna Kim.

  1. 1. Micro-scale Platforms for Investigations of Biological Structures

    Författare :Anna Kim; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; microfabrication; non-ionic surfactants; single-cell viability; hydrodynamic flow confinement; cell-to-cell connections; SU-8; Teflon AF; cell protrusions; free-standing probes; millimeter-waves;

    Sammanfattning : This thesis describes the development of innovative micro-scale platforms as a means to address the current challenges within the field of cell biology, and to provide an interface between miniaturized analytical technology and experimental systems for the life sciences. The work includes an analytical platform for rapid assessment of the viability of adherent single cells; a surface patterning strategy for investigations of cell-to-cell communication via protrusions; a versatile microfluidic probe in SU-8 hard-polymer, and a microfabricated millimeter-wave measurement system for the identification and characterization of niosome (non-ionic surfactant vesicle) constituents, which is operated in a label-free, non-invasive manner. LÄS MER

  3. 2. In vitro and in silico Predictions of Hepatic Transporter-Mediated Drug Clearance and Drug-Drug Interactions in vivo

    Författare :Anna Vildhede; Per Artursson; Maria Karlgren; Maria Kjellsson; Ulf Norinder; Kim Brouwer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; OATP1B1; OATP1B3; OATP2B1; NTCP; drug transporters; human hepatocytes; atorvastatin; pitavastatin; proteomics; sandwich-cultured human hepatocytes; SCHH; mechanistic modeling; in vitro-in vivo extrapolation; transport inhibition; hepatic uptake; hepatocyte isolation; transporter contribution; Biopharmaceutics; Biofarmaci;

    Sammanfattning : The liver is the major detoxifying organ, clearing the blood from drugs and other xenobiotics. The extent of hepatic clearance (CL) determines drug exposure and hence, the efficacy and toxicity associated with exposure. Drug-drug interactions (DDIs) that alter the hepatic CL may cause more or less severe outcomes, such as adverse drug reactions. LÄS MER

  4. 3. Gränsland : Svensk ungdomsvård mellan vård och straff

    Författare :Kim Silow Kallenberg; Ann Runfors; Jenny Gunnarsson Payne; Anna Sofia Lundgren; Södertörns högskola; []
    Nyckelord :HUMANIORA; HUMANITIES; compulsory care; institutions; ethnography; staff; logic; fantasy; post-structuralism; masculinity; subject position; age; class; power; powerlessness; tvångsvård; institutioner; etnografi; personal; logik; fantasi; poststrukturalism; maskulinitet; subjektsposition; ålder; klass; makt; maktlöshet; Historical Studies; Historiska studier;

    Sammanfattning : Borderlands. Swedish youth care in the intersections of care and punishmentThis dissertation concerns staff working in special residential homes, or secure units, for boys and young men and, less specifically, the compulsory care of problematic teenagers. LÄS MER

  5. 4. Galna kameror och barns virtuella bildseende, bildtänkande och filmgörande i förskolan

    Författare :Maria Olsson; Anne-Li Lindgren; Anna Palmer; Simon Ceder; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; children; preschool; children’s filmmaking; image vision; digital videography; Deleuze’s film philosophy; transcendental empiricism; the crystal-image; barn; förskola; barns filmgörande; bildseende; digital videografi; Deleuzes filmfilosofi; transcendental empirism; kristallbild; Early Childhood Education; förskoledidaktik;

    Sammanfattning : The aim of this thesis is to contribute knowledge about children’s image-vision, image-thinking and image- and filmmaking in preschool, through a collaboration with children and digital film technology, and about Gilles Deleuze’s film philosophy (1989) as well as digital videography and the methodology created in the research process. The empirical production was carried out as a digital decentralized videography, according to Pink et al. LÄS MER