Sökning: "Animal models"
Visar resultat 1 - 5 av 759 avhandlingar innehållade orden Animal models.
1. Novel Treatment Modalities for High-Risk Neuroblastoma : Studies in Animal Models
Sammanfattning : Neuroblastoma, the most common extracranial solid tumor of childhood, is a heterogeneous tumor. In some patients, the tumor can go into spontaneous regression and disappear whereas other patients have rapidly growing tumors with a poor prognosis. LÄS MER
2. Assessment of eosinophil degranulation in allergic diseases and experimental models
Sammanfattning : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. LÄS MER
3. Hantaviruses : animal models, immunology and pathogenesis
Sammanfattning : Hantaviruses cause two serious and often fatal human zoonotic diseases: hemorrhagic fever with renal syndrome (HFRS) in Eurasia, and hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Hantaviruses are rodent-borne and are transmitted to humans via inhalation of contaminated rodent excreta. LÄS MER
4. Genetic Heteroscedasticity for Domestic Animal Traits
Sammanfattning : Animal traits differ not only in mean, but also in variation around the mean. For instance, one sire’s daughter group may be very homogeneous, while another sire’s daughters are much more heterogeneous in performance. The difference in residual variance can partially be explained by genetic differences. LÄS MER
5. From disease to genes in animal models of rheumatoid arthritis and multiple sclerosis
Sammanfattning : Rheumatoid arthritis (RA) and multiple sclerosis (MS) are complex inflammatory autoimmune diseases. The aetiology is largely unknown but the risk of developing disease is dependent on both genetic and environmental factors. LÄS MER