Sökning: "Alexandra Patriksson"

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  1. 1. From Solution into Vacuum - Structural Transitions in Proteins

    Författare :Alexandra Patriksson; David van der Spoel; Carol Robinson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular dynamics; computer simulations; mass spectrometry; electrospray ionization; free-electron laser; vacuum structure of proteins; solvation; desolvation; single molecule imaging; Chemistry; Kemi;

    Sammanfattning : Information about protein structures is important in many areas of life sciences, including structure-based drug design. Gas phase methods, like electrospray ionization and mass spectrometry are powerful tools for the analysis of molecular interactions and conformational changes which complement existing solution phase methods. LÄS MER