Sökning: "Age of onset"
Visar resultat 16 - 20 av 610 avhandlingar innehållade orden Age of onset.
16. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet
Sammanfattning : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). LÄS MER
17. Histopathological and immunocytochemical studies in age-associated dementias : the importance of rigorous histopathological criteria for classification of progressive dementia disorders
Sammanfattning : Dementia is an age-associated organic brain disorder, recognizable by the essential features of psychological or behavioral abnormality associated with permanent dysfunction of the brain interfering with social and occupational functioning.There are two clinical and three histopathological forms of dementia 1) primary degenerative dementia, (PDD), or Alzheimer's dementia/Senile dementia of Alzheimers type (AD/SDAT) which is associated with clinical features of uniform progression and insidious onset of symptoms and histopathologically i- dentified by the occurrence of neurofibrillary tangles (NFT) and senile/neuritic plaques (SP/NP) in various cortical and subcor- tical regions; 2) vascular dementia, or multi-infarct dementia (MID), which is associated with clinical features of stepwise progress and patchy distribution of deficits, and histopathologically identified by the occurrence of multiple large and/or small haemorrhagic and/or ischaemic infarcts in various cortical and subcortical regions and 3) intermediate form of dementia or "mixed” ("combined") dementia (AD-MID), which is histopatho- logically associated with the coexistance of symptoms and lesions observed in AD/SDAT and MID, and clinically referred to the MID group. LÄS MER
18. Aspects of the etiology of gastric adenocarcinoma
Sammanfattning : Gastric adenocarcinoma is the fourth most common malignancy and the second leading cause of cancer death in the world. Tremendous effort has been made to look into the causation of gastric cancer. Etiological research plays a key role in identifying possible preventive and interventional measures. LÄS MER
19. Demographic and clinical characteristics in groups of individual with exessive alcohol intake
Sammanfattning : People who misuse alcohol are a heterogeneous group with different etiology and clinical characteristics. One aim in the field of alcohol research has been to categorise these individuals in order to study possible pathways into alcohol use disorders and the long-term course of alcoholism. LÄS MER
20. Towards systematic prevention of athletics injuries : Use of clinical epidemiology for evidence-based injury prevention
Sammanfattning : The aims of this thesis were to outline the design protocol for a prospective clinical epidemiological study of injuries among athletics athletes; study the 1-year prevalence, the point prevalence and incidence of injuries in total cohorts of Swedish elite adult and talented youth athletics athletes; pinpoint the risk indicators and factors for different injury types/patterns in athletics.In paper I, an argument-based method to investigate complex design problems was used to structure the collection and analysis of data. LÄS MER