Sökning: "Activated protein c resistance"

Visar resultat 11 - 15 av 42 avhandlingar innehållade orden Activated protein c resistance.

  1. 11. Time-resolved X-ray diffraction and solution scattering studies of Sensory Rhodopsin II in isolation and in complex with its transducer

    Författare :Giorgia Ortolani; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; light-activated membrane protein; microbial Rhodopsins; Sensory rhodopsin II; SRII; SRII:HtrII; transducer; SSX; XSS; time-resolved;

    Sammanfattning : Light is an important source of energy for many living organisms. Many life forms have therefore evolved cellular receptors that are able to sense light and thereby optimise conditions for photosynthesis and pho- totrophy. LÄS MER

  3. 12. Unstable coronary artery disease : Studies on inflammation, infection, hemostasis, and the effects of low-molecular-mass heparin treatment

    Författare :Henrik Toss; Uppsala universitet; []
    Nyckelord :Medical sciences; unstable angina; myocardial infarction; prognosis; inflammation; hemostasis; fibrinolysis; resistance to activated protein C. low-molecular-mass heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The occurrence and prognostic importance, of inflammatory activity, signs of Chlamydia pneumoniae infection. APC resistance, hemostasis, and the effects of low-molecular-mass heparin (LMMH) was evaluated in patients with unstable coronary artery disease (UCAD). LÄS MER

  4. 13. The regulatory role of microRNA in human adipocytes and their link to insulin resistance

    Författare :Yasmina Belarbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. LÄS MER

  5. 14. Diabetogenic effects of glucocorticoids : role of protein phosphatase 5 and GLP-1 receptor activation

    Författare :Liselotte Fransson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity, the metabolic syndrome and type 2 diabetes are inextricably linked together, and all increase with rapid pace globally. Glucocorticoid (GC) excess is associated with diabetogenic effects, including insulin resistance and glucose intolerance, and a role for GCs has also been proposed in the development and pathology of the metabolic syndrome. LÄS MER

  7. 15. Structural and functional studies of factor V in health and disease

    Författare :Mårten Steen; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; APC resistance and hemophilia; thrombosis; factor VIII; coagulation; factor V;

    Sammanfattning : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. LÄS MER