Sökning: "APC-PCI complex."

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden APC-PCI complex..

1. 1. Circulating biomarkers in patients with abdominal aortic aneurysm

   Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

   Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER

3. 2. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

   Författare :Johan Elf; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; APC-PCI complex.; D-Dimer; Clinical probability; Diagnosis;

   Sammanfattning : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. LÄS MER

4. 3. Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

   Författare :Gunnar Nilsson; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; protein C; mortality; intensive care; health economics; global haemostatic tests; blood coagulation disorders; APC-PCI complex; abdominal aortic aneurysm operation; antithrombin; Medicin människa och djur ;

   Sammanfattning : Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. LÄS MER

5. 4. Development of Methods for Measuring Protein C Inhibitor and Antithrombin: Use of Monoclonal Antibodies against the Reactive Center Loop-Inserted Forms of the Serpins

   Författare :Margareta Kjellberg; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; monoclonal antibody; latent antithrombin; immunoassay; cleaved PCI; cleaved antithrombin; Antithrombin; APC-PCI complex;

   Sammanfattning : Protein C inhibitor (PCI) and antithrombin (AT) are serine protease inhibitors (serpins) that are involved in the regulation of coagulation. Like other inhibitory serpins, PCI and AT adopt different structural conformations that are related to their functions. LÄS MER

7. 5. Development of a Method to Measure Plasma Levels of Activated Protein C in Complex with Protein C Inhibitor

   Författare :Karin Strandberg; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C inhibitor; activated protein C; hypercoagulability; deep vein thrombosis; Clinical chemistry; myocardial infarction; Klinisk kemi;

   Sammanfattning : Acute myocardial infarction (MI) and deep venous thrombosis (DVT) are conditions caused by thrombus formation with activation of the coagulation system. The plasma concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI), APC–PCI complex is increased in such states. LÄS MER