Sökning: "AAT"
Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet AAT.
1. Chronic Obstructive Pulmonary Disease: Role of Alpha-1-antitrypsin
Sammanfattning : The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. LÄS MER
2. Serine protease inhibitors in the upper and lower airways
Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER
3. Beta Cell Function: from Human Genetics to Animal Models
Sammanfattning : Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. LÄS MER
4. Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID
Sammanfattning : Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. LÄS MER
5. Characterization and design of printed RFID solutions
Sammanfattning : .... LÄS MER