Sökning: "AA-amyloid"

Hittade 5 avhandlingar innehållade ordet AA-amyloid.

  1. 1. Deposition and Resolution of AA Amyloid

    Författare :Sofia N. Nyström; Gunilla T Westermark; Christoph Röcken; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AA-amyloid; autophagy; resolution; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi;

    Sammanfattning : Amyloidosis is a group of protein misfolding diseases characterized by extracellulardeposition of fibrillar protein aggregates. Today more than 25 different human amyloidogenicproteins have been identified, causing a variety of pathological conditions that includeAlzheimer’s disease, type 2 diabetes and prion diseases. LÄS MER

  3. 2. The Importance of Macrophages, Lipid Membranes and Seeding in Experimental AA Amyloidosis

    Författare :Aida Vahdat Shariatpanahi; Karin Öllinger; Katarzyna Lundmark; Gunilla Westermark; Elin Esbjörner Winters; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Amyloidosis is a group of protein misfolding diseases caused by tissue deposition of fibrillary protein aggregates termed amyloid. Amyloid A (AA) amyloidosis is a systemic form of amyloidosis that occurs as a complication of chronic inflammatory diseases, such as rheumatoid arthritis, familial Mediterranean fever and chronic infections, such as tuberculosis. LÄS MER

  4. 3. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases

    Författare :Andreas Digre; Jin-Ping Li; Lena Kjellén; Liliana Schaefer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Heparan sulfate; Inflammation; Inflammatory diseases; Autoimmune diseases; Amyloidosis; Reumathoid arthritis; SAA; APP; A beta; Neuroinflammation; Medical Science; Medicinsk vetenskap; Medical Biochemistry; Medicinsk biokemi; Immunologi; Immunology; Neurology; Neurologi;

    Sammanfattning : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. LÄS MER

  5. 4. Medin amyloid - a matter close to the heart : Studies on medin amyloid formation and involvement in aortic pathology

    Författare :Annika Larsson; Per Westermark; Sari Kiuru-Enari; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AA amyloidosis; aging; amyloid; aneurysm; arterial media; dissection; elastin; medin amyloid; lactadherin; thoracic aorta; Pathology; Patologi;

    Sammanfattning : Amyloidoses are a group of protein misfolding diseases characterized by deposits of insoluble fibrillar protein aggregates. Medin amyloid, which is the focus of this thesis, appears in the media of the thoracic aorta in nearly all individuals over 50 years. LÄS MER

  7. 5. Studies on Pathogenesis of Experimental AA Amyloidosis : Effects of Amyloid Enhancing Factor and Amyloid-Like Fibrils in Rapid Amyloid Induction

    Författare :Katarzyna Lundmark; D. Carleton Gajdusek; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Amyloidosis is a group of diseases, caused by an extracellular deposition of a characteristic proteinaceous material, amyloid, in various organs. Fibril formation occurs in all of amyloid related diseases, making it a crucial mechanism to understand. LÄS MER