Sökning: "5-HTTLPR"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet 5-HTTLPR.

  1. 1. A Biopsychosocial and Long Term Perspective on Child Behavioral Problems : Impact of Risk and Resilience

    Författare :Sara Agnafors; Carl Göran Svedin; Gunilla Sydsjö; Anders Broberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 5-HTTLPR; BDNF Val66Met; maternal mental health; adversities; resilience; children;

    Sammanfattning : Mental health has become a prominent issue in society. Yet, much remains unknown about the etiology of psychiatric disorders. The aim of the present thesis was to investigate the association between biological, psychological and social factors of risk and resilience and behavioral problems in a birth cohort of Swedish children. LÄS MER

  2. 2. On the influence of serotonin- and sex steroid-related genetic variation on mood, anxiety, personality, autism and transsexualism

    Författare :Susanne Henningsson; Göteborgs universitet; []
    Nyckelord :serotonin; 5-HTTLPR; TPH2; 5-HT3; sex steroids; androgen receptor; estrogen receptor; genetics; gene-gene interaction; social phobia; anxiety; premenstrual dysphoric disorder; depression; personality; autism; transsexualism; amygdala; emotional perception; life events;

    Sammanfattning : Background: The neurotransmitter serotonin has been related to mood and anxiety, and variation in genes that encode important members of the serotonergic system may hence affect mood- and anxiety-related traits. Sex steroids influence brain development, and variation in genes encoding androgen and estrogen receptors, or enzymes needed for sex steroid synthesis, may be of importance for both personality traits and risk for psychiatric disorders. LÄS MER

  3. 3. Genetic gating of human fear, fear learning and extinction : psychophysiological, brain imaging (fMRI) and clinical studies

    Författare :Tina B Lonsdorf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Individuals differ in their reaction to the same environmental stressor. After being opposed to the same trauma, some individuals will develop affective pathologies, while others will not. This is assumed to result, at least partly, from a differential genetic vulnerability. LÄS MER

  4. 4. Molecular imaging of the serotonin system in human behaviour

    Författare :Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

    Sammanfattning : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. LÄS MER

  5. 5. Influence of serotonin-related genes on behavior and body weight

    Författare :Jessica Bah Rösman; Göteborgs universitet; []
    Nyckelord :Serotonin; Genes; anorexia nervosa; premenstrual dysforia; body weight; suicide; polymorphism; HTR2C; SLC6A4; GATA2; HTR3B;

    Sammanfattning : Rationale: The neurotransmitter serotonin has been implicated in the regulation of normal behaviors, including food intake, and attributed importance for a variety of common psychiatric conditions, including major depression, suicidal behavior, eating disorders and premenstrual dysphoria. The purpose of these studies was to explore the possible influence of genetic variation in serotonin-related genes on a) body weight, b) binding capacity of the serotonin transporter in the brain of suicide attempters and c) a disorder for which numerous findings suggest serotonin to play a key role, i. LÄS MER