Sökning: "123I-FP-Cit"
Hittade 3 avhandlingar innehållade ordet 123I-FP-Cit.
1. Nuclear medicine methods in idiopathic Parkinsonism : pre- and postsynaptic dopamine SPECT
Sammanfattning : Background: Single photon emission computed tomography (SPECT) with dopamine transporter (DAT) and dopamine D2 receptor (D2R) ligands can visualise the integrity of the nigrostriatal dopamine system. Parkinson’s disease (PD) and the atypical parkinsonian diseases (APD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), have similar symptoms and dopamine depletion, but differ in pharmacological response and prognosis. LÄS MER
2. Towards Clinical Implementation of Dynamic Positron Emission Tomography in Neurodegenerative Diseases
Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders worldwide. Positron emission tomography (PET), together with suitable biomarkers, can aid in the clin-ical evaluation as well as in research investigations of these diseases. LÄS MER
3. Validation of a novel PET imaging marker for dopaminergic degeneration in Parkinson’s disease patients
Sammanfattning : Background: There is a need for an objective disease progression marker for Parkinson’s disease (PD). DAT measurement with PET-radioligand [18F]FE-PE2I has so far shown to be promising with its favorable kinetics, low production of metabolites, and ability to image the whole nigrostriatal pathway. LÄS MER