Sökning: "11β-Hydroxysteroid Dehydrogenase Type 1"
Hittade 3 avhandlingar innehållade orden 11β-Hydroxysteroid Dehydrogenase Type 1.
1. Adipose tissue as an active organ : blood flow regulation and tissue-specific glucocorticoid metabolism
Sammanfattning : Background: Despite advances in the treatment of atherosclerosis, cardiovascular disease is the leading cause of death worldwide. With the population getting older and more obese, the burden of cardiovascular disease may further increase. LÄS MER
2. Estrogen and Glucocorticoid Metabolism
Sammanfattning : Background: Cardiovascular disease (CVD) is the leading cause of death among women in Sweden. The risk of CVD increases rapidly after the menopause. A major contributing factor may be the redistribution of adipose tissue, from the peripheral to central depots, associated with menopause. LÄS MER
3. Disturbed Islet Function and Alterations in Islet Protein Expression
Sammanfattning : Pancreatic β-cells sense the concentration of glucose in the systemic circulation through metabolism of the sugar molecule. Failure to correlate the blood sugar concentration to an appropriate metabolic signal disrupts the function of the β-cell as a controller of glucose homeostasis and may contribute to the development of type 2 diabetes mellitus. LÄS MER